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Combo-pilling may be the newest fad or also the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular may be the fact that since right now there aren't long term prescription diet pills that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and must not be taken in people with seizure disorders. The drug also can raise blood pressure and heartbeat, and really should not be used in people with a history of cardiac arrest or stroke in the previous six months. 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